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Cellosaurus AO-40.10 (CVCL_C6WR)

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Cell line name AO-40.10
Synonyms AO-40
Accession CVCL_C6WR
Resource Identification Initiative To cite this cell line use: AO-40.10 (RRID:CVCL_C6WR)
Comments Characteristics: Hybrid of the T-cell hybridoma FS6-14.13 Ag2.1 with T-cell blasts from chicken ovalbumin (cOVA)-immunized B10.A (H-2a) mice. Produces IL-2 in response to antigen stimulation (ovalbumin) plus irradiated B10.A spleen cells (PubMed=6166712).
Doubling time: ~12 hours (PubMed=6166712).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_M112 (FS6-14.13 Ag2.1)
Category Hybridoma
Publications

PubMed=6166712; DOI=10.1084/jem.153.5.1198; PMCID=PMC2186156
John Wayne Kappler, Barry Skidmore, Janice White, Philippa Marrack;
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.
J. Exp. Med. 153:1198-1214(1981)

PubMed=32419056; DOI=10.1007/s00005-020-00579-1
Janice White, Rebecca L. O'Brien, Willi K. Born;
BW5147 and derivatives for the study of T cells and their antigen receptors.
Arch. Immunol. Ther. Exp. 68:15-15(2020)

Cross-references
Encyclopedic resources Wikidata; Q117704193
Entry history
Entry creation21-Mar-2023
Last entry update29-Jun-2023
Version number2