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Cellosaurus MG-63/MTXR8 (CVCL_C6UY)

[Text version]
Cell line name MG-63/MTXR8
Accession CVCL_C6UY
Resource Identification Initiative To cite this cell line use: MG-63/MTXR8 (RRID:CVCL_C6UY)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0426 (MG-63)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=36480329; DOI=10.1002/adbi.202200194
Kaan Low, Frank Hills, Helen C. Roberts, Britta Stordal;
Establishment and characterization of single and triple-agent resistant osteosarcoma cell lines.
Adv. Biol. (Weinh.) 7:e2200194.1-e2200194.13(2023)

Cross-references
Encyclopedic resources Wikidata; Q117704698
Entry history
Entry creation21-Mar-2023
Last entry update19-Dec-2024
Version number3