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Cellosaurus HROG02-CIITA (CVCL_C6JW)

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Cell line name HROG02-CIITA
Accession CVCL_C6JW
Resource Identification Initiative To cite this cell line use: HROG02-CIITA (RRID:CVCL_C6JW)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7067; CIITA.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Omics: Proteomics; HLA class I peptidome.
Omics: Proteomics; HLA class II peptidome.
Derived from site: In situ; Brain, right parieto-occipital lobe.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4U38 (HROG02)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=33592498; DOI=10.1074/mcp.RA120.002201; PMCID=PMC8724627
Greta Forlani, Justine Michaux, HuiSong Pak, Florian Huber, Elodie Lauret Marie-Joseph, Elise Ramia, Brian J. Stevenson, Michael Linnebacher, Roberto S. Accolla, Michal Bassani-Sternberg;
CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens.
Mol. Cell. Proteomics 20:100032.1-100032.21(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049504
Proteomic databases PRIDE; PXD020079
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number7