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Cellosaurus GSC-326 (CVCL_C6IR)

[Text version]
Cell line name GSC-326
Accession CVCL_C6IR
Resource Identification Initiative To cite this cell line use: GSC-326 (RRID:CVCL_C6IR)
Comments Group: Cancer stem cell line.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Mesenchymal stem cell; CL=CL_0000134.
Disease Malignant glioma (NCIt: C4822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6J4 (GSC-326/ALDH1A3-KO.1.1)CVCL_C6J5 (GSC-326/ALDH1A3-KO.2.3)CVCL_C6J6 (GSC-326/ALDH1A3-KO.2.4)
CVCL_C6J7 (GSC-326/ALDH1A3-KO.3.1)CVCL_C6J8 (GSC-326/ALDH1A3-KO.3.4)CVCL_C6J9 (GSC-326/ALDH1A3-KO.3.5)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=23650391; DOI=10.1073/pnas.1221478110; PMCID=PMC3666732
Ping Mao, Kaushal Joshi, Jian-Feng Li, Sung-Hak Kim, Pei-Pei Li, Lucas Santana-Santos, Soumya Luthra, Uma R. Chandran, Panayiotis V. Benos, Luke Smith, Mao-De Wang ...Show all 15 authors... , Bo Hu, Shi-Yuan Cheng, Robert William Sobol, Ichiro Nakano; Show fewer authors
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
Proc. Natl. Acad. Sci. U.S.A. 110:8644-8649(2013)

PubMed=34934174; DOI=10.1038/s42003-021-02949-7; PMCID=PMC8692581
Jian-Feng Li, Silvia Garavaglia, Zhao-Feng Ye, Andrea Moretti, Olga V. Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V. Klyuyeva, Kelli R. Goggans ...Show all 20 authors... , Natalia Y. Kedishvili, E. Alan Salter, Andrzej Wierzbicki, Marie E. Migaud, Steven J. Mullett, Nathan A. Yates, Carlos J. Camacho, Menico Rizzi, Robert William Sobol; Show fewer authors
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Commun. Biol. 4:1420.1-1420.16(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049089
Proteomic databases PRIDE; PXD028125
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3