Cellosaurus cell line 2Y-3t (CVCL

Cellosaurus 2Y-3t (CVCL_C6GE)

Cross-references
Cell line name	2Y-3t
Accession	CVCL_C6GE
Resource Identification Initiative	To cite this cell line use: 2Y-3t (RRID:CVCL_C6GE)
Comments	Characteristics: Composed of bipotent neural progenitor cells capable of generating both neurons and oligodendrocytes. Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53. Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037. Cell type: Neural progenitor cell; CL=CL_0011020.
Disease	Mouse cerebellar neoplasm (NCIt: C191764)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 x CBA Trp53-/-.
Originate from same individual	CVCL_C6GF ! 2Y-6f1
Sex of cell	Male
Age at sampling	Adult
Category	Cancer cell line
Publications	PubMed=9824692; DOI=10.1016/S0006-8993(98)00979-2 Masanobu Minakawa, Takashi Sugimoto, Shin-ichi Aizawa, Yasuhiro Tomooka; Cerebellar cell lines established from a p53-deficient adult mouse. Brain Res. 813:172-176(1998) PubMed=12270117; DOI=10.1016/S0006-291X(02)02225-8 Mitsutoshi Tominaga, Yasuhiro Tomooka; Novel genes cloned from a neuronal cell line newly established from a cerebellum of an adult p53(-/-) mouse. Biochem. Biophys. Res. Commun. 297:473-479(2002) PubMed=15978002; DOI=10.1111/j.1460-9568.2005.04119.x Mitsutoshi Tominaga, Shinya Honda, Atsumasa Okada, Akifumi Ikeda, Seiji Kinoshita, Yasuhiro Tomooka; A bipotent neural progenitor cell line cloned from a cerebellum of an adult p53-deficient mouse generates both neurons and oligodendrocytes. Eur. J. Neurosci. 21:2903-2911(2005)
Encyclopedic resources	Wikidata; Q116048070
Entry history
Entry creation	15-Dec-2022
Last entry update	29-Jun-2023
Version number	3