Cellosaurus logo
expasy logo

Cellosaurus INT-MEL-17 (CVCL_C680)

[Text version]
Cell line name INT-MEL-17
Synonyms Me4405; ME4405; ME-4405; ME 4405
Accession CVCL_C680
Resource Identification Initiative To cite this cell line use: INT-MEL-17 (RRID:CVCL_C680)
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C688 ! LCL4405
Sex of cell Female
Age at sampling 83Y
Category Cancer cell line
Publications

PubMed=8459226; DOI=10.1084/jem.177.4.989; PMCID=PMC2190978
Andrea Anichini, Cristina Maccalli, Roberta Mortarini, Stefania Salvi, Arabella Mazzocchi, Paola Squarcina, Meenhard Herlyn, Giorgio Parmiani;
Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients.
J. Exp. Med. 177:989-998(1993)

PubMed=7520026; DOI=10.1002/ijc.2910580413
Peter Hersey, Zhao-Yi Si, Melanie J. Smith, Wayne D. Thomas;
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-#
Wayne D. Thomas, Melanie J. Smith, Zhao-Yi Si, Peter Hersey;
Expression of the co-stimulatory molecule CD40 on melanoma cells.
Int. J. Cancer 68:795-801(1996)

PubMed=9725211; DOI=10.4049/jimmunol.161.5.2195
Wayne D. Thomas, Peter Hersey;
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells.
J. Immunol. 161:2195-2200(1998)

DOI=10.1007/0-306-46872-7_16
Andrea Anichini, Roberta Mortarini, Claudia Vegetti, Alessandra Molla, Alessandra Borri, Giorgio Parmiani;
Melanoma: the Milan melanoma cell lines.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.283-292; Kluwer Academic Publishers; New York; USA (1999)

PubMed=10338330; DOI=10.1097/00008390-199902000-00003
Helen Rizos, Artur P. Darmanian, James O. Indsto, Jenniffer A. Shannon, Richard F. Kefford, Graham J. Mann;
Multiple abnormalities of the p16INK4a-pRb regulatory pathway in cultured melanoma cells.
Melanoma Res. 9:10-19(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O'Connor, Michael O'Rourke, Richard Anthony Scolyer ...Show all 15 authors... , Graham J. Mann, Christopher W. Schmidt, Adrian Herington, Nicholas K. Hayward; Show fewer authors
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=22553342; DOI=10.1158/1078-0432.CCR-11-2232; PMCID=PMC3426233
Elena Tassi, Marina Zanon, Claudia Vegetti, Alessandra Molla, Ilaria Bersani, Valentina Perotti, Marzia Pennati, Nadia Zaffaroni, Michele Milella, Soldano Ferrone, Carmelo Carlo-Stella ...Show all 14 authors... , Alessandro M. Gianni, Roberta Mortarini, Andrea Anichini; Show fewer authors
Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways.
Clin. Cancer Res. 18:3316-3327(2012)

DOI=10.13130/grazia-giulia_phd2016-02-18
Giulia Grazia;
Co-targeting of oncogenic and death receptors pathways in human melanoma: pre-clinical rationale for a pro-apoptotic and anti-angiogenic strategy.
Thesis PhD (2015); Universita degli studi di Milano; Milano; Italy

Cross-references
Cell line databases/resources cancercelllines; CVCL_C680
Anatomy/cell type resources BTO; BTO_0005716
Encyclopedic resources Wikidata; Q54897764
Gene expression databases GEO; GSM1403049
GEO; GSM1403050
GEO; GSM1403051
GEO; GSM1403052
GEO; GSM1403053
GEO; GSM1403054
Polymorphism and mutation databases Cosmic; 889008
Cosmic; 929202
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number19