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Cellosaurus UKRV-Mel-12b (CVCL_C660)

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Cell line name UKRV-Mel-12b
Accession CVCL_C660
Resource Identification Initiative To cite this cell line use: UKRV-Mel-12b (RRID:CVCL_C660)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.228_229CC>TT (-124/-125CC>TT); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C659 ! UKRV-Mel-12a
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-224

Markers:
AmelogeninX
CSF1PO11,12
D3S135815,18
D5S81812
D7S8208,11
D13S3178,11
FGA22,25
TH017,9.3
TPOX8,9
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C660
ESTDAB; ESTDAB-224
Encyclopedic resources Wikidata; Q54990569
Polymorphism and mutation databases Cosmic; 1846698
Cosmic; 2686511
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number14