| Cell line name |
FM86 |
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| Synonyms |
FM-86 |
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| Accession |
CVCL_C610 |
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| Resource Identification Initiative |
To cite this cell line use: FM86 (RRID:CVCL_C610) |
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| Comments |
Omics: Variations; Array-based CGH. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg58Ter (c.171_172CC>TT) (p.Pro72Leu, c.214_215CC>TT); Zygosity=Unspecified (PubMed=23851445).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (PubMed=23851445).
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| HLA typing |
Source: PubMed=15592718
| Class I | | HLA-A | A*02:01 | | HLA-B | B*15:01:01:01,44:02 | | HLA-C | C*03:04,05:01 | | Class II | | HLA-DP | DPB1*04:01 | | HLA-DQ | DQB1*03:02,03:01:01 |
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| Disease |
Cutaneous melanoma (NCIt: C3510) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
Age unspecified |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): ESTDAB=ESTDAB-028
Markers:
Run an STR similarity search on this cell line |
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| Publications | PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005) PubMed=17260012; DOI=10.1038/sj.onc.1210252
Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M., Guldberg P., Borg A.
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007) PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_C610
ESTDAB; ESTDAB-028
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| Encyclopedic resources |
Wikidata; Q54835068
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| Gene expression databases |
GEO; GSM156035
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| Polymorphism and mutation databases |
Cosmic; 1047680
Cosmic; 2163779
IARC_TP53; 26106
Progenetix; CVCL_C610
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 19 |
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