Cellosaurus cell line NCC-PS1-C1 (CVCL

Cellosaurus NCC-PS1-C1 (CVCL_C5Z2)

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Cell line name

NCC-PS1-C1

Accession

CVCL_C5Z2

Resource Identification Initiative

To cite this cell line use: NCC-PS1-C1 (RRID:CVCL_C5Z2)

Comments

Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 39 hours (PubMed=36103079).
Omics: Phenotyping; Drug screening.
Omics: Variations; SNP array analysis.
Misspelling: NCC-PS-C1; Note=In Cellosaurus releases 44 to 47.
Derived from site: In situ; Popliteal fossa, hypodermis; UBERON=UBERON_0013069+UBERON_0002072.

Sequence variations

Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Cys72Ter (c.216C>A); Zygosity=Unspecified (PubMed=36103079).
Mutation; HGNC; HGNC:7883; NOTCH3; Simple; p.Arg1873Cys (c.5617C>T); ClinVar=VCV000932356; Zygosity=Unspecified (PubMed=36103079).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=36103079).

Disease

Undifferentiated pleomorphic sarcoma (NCIt: C4247)
Undifferentiated pleomorphic sarcoma (ORDO: Orphanet_2023)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

72Y

Category

Cancer cell line

STR profile

Source(s): PubMed=36103079

Markers:

Amelogenin	X
CSF1PO	12
D5S818	11,12
D7S820	8,12
D13S317	13
D16S539	12
D21S11	31
TH01	9
TPOX	11
vWA	17,18,19

Publications

PubMed=36103079; DOI=10.1007/s13577-022-00787-1
Taro Akiyama, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Ryuto Tsuchiya, Takuya Ono, Jun Sugaya, Eisuke Kobayashi, Akihiko Yoshida, Seiji Ohtori, Akira Kawai, Tadashi Kondo;
Establishment and characterization of NCC-PS1-C1: a novel cell line of pleomorphic sarcoma from a patient after neoadjuvant radiotherapy.
Hum. Cell 35:2011-2019(2022)

Cross-references

Encyclopedic resources

Wikidata; Q116049882

Entry history

Entry creation

15-Dec-2022

Last entry update

27-Nov-2025

Version number