Cellosaurus cell line NCC-PLPS2-C1 (CVCL

Cellosaurus NCC-PLPS2-C1 (CVCL_C5Z1)

[Text][XML][JSON]

Cell line name

NCC-PLPS2-C1

Accession

CVCL_C5Z1

Resource Identification Initiative

To cite this cell line use: NCC-PLPS2-C1 (RRID:CVCL_C5Z1)

Comments

Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 24 hours (PubMed=36436139).
Omics: Phenotyping; Drug screening.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Foot, hypodermis; UBERON=UBERON_0002387+UBERON_0002072.

Sequence variations

Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Unspecified (PubMed=36436139).
Mutation; HGNC; HGNC:9585; PTCH1; Simple; p.Glu44Gly (c.131A>G); ClinVar=VCV000041768; Zygosity=Unspecified (PubMed=36436139).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>A); ClinVar=VCV001453627; Zygosity=Unspecified (PubMed=36436139).

Disease

Pleomorphic liposarcoma (NCIt: C3705)
Pleomorphic liposarcoma (ORDO: Orphanet_99969)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

84Y

Category

Cancer cell line

STR profile

Source(s): PubMed=36436139

Markers:

Amelogenin	X,Y
CSF1PO	12
D5S818	9,10
D7S820	11
D13S317	8,12
D16S539	9
D21S11	29,30
TH01	6,7
TPOX	8
vWA	17,18

Publications

PubMed=36436139; DOI=10.1007/s13577-022-00828-9
Taro Akiyama, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Julia Osaki, Yuki Adachi, Takuya Ono, Ryuto Tsuchiya, Chiaki Sato, Shintaro Iwata, Naoki Kojima ...Show all 15 authors... , Akihiko Yoshida, Seiji Ohtori, Akira Kawai, Tadashi Kondo; Show fewer authors
Establishment and characterization of NCC-PLPS2-C1: a novel cell line of pleomorphic liposarcoma.
Hum. Cell 36:468-475(2023)

Cross-references

Encyclopedic resources

Wikidata; Q116049881

Entry history

Entry creation

15-Dec-2022

Last entry update

10-Apr-2025

Version number