Cellosaurus cell line C1R-B*27:05 (CVCL

Cellosaurus C1R-B*27:05 (CVCL_C5VE)

Cross-references
Cell line name	C1R-B*27:05
Synonyms	C1R05
Accession	CVCL_C5VE
Resource Identification Initiative	To cite this cell line use: C1R-B*27:05 (RRID:CVCL_C5VE)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4932; HLA-B (Note=Allele B*27:05). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_3714 (HMy2.C1R)
Sex of cell	Female
Age at sampling	33Y
Category	Transformed cell line
Publications	PubMed=1692072; DOI=10.4049/jimmunol.144.10.4038 Victor Calvo, Susana Rojo, Daniel Lopez, Begona Galocha, Jose Antonio Lopez de Castro; Structure and diversity of HLA-B27-specific T cell epitopes. Analysis with site-directed mutants mimicking HLA-B27 subtype polymorphism. J. Immunol. 144:4038-4045(1990) PubMed=25469497; DOI=10.1002/art.38980 Alejandro Sanz-Bravo, Jose Campos, Marina S. Mazariegos, Jose Antonio Lopez de Castro; Dominant role of the ERAP1 polymorphism R528K in shaping the HLA-B27 peptidome through differential processing determined by multiple peptide residues. Arthritis Rheumatol. 67:692-701(2015)
Encyclopedic resources	Wikidata; Q116048628
Proteomic databases	PRIDE; PXD008500
Entry history
Entry creation	15-Dec-2022
Last entry update	27-Nov-2025
Version number	8