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Cellosaurus LG2-MEL (CVCL_C5U8)

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Cell line name LG2-MEL
Synonyms LG-2-MEL
Accession CVCL_C5U8
Resource Identification Initiative To cite this cell line use: LG2-MEL (RRID:CVCL_C5U8)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:16994; OS9; Simple; p.Pro446Leu (c.1337C>T); Zygosity=Heterozygous (PubMed=12747754).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C5UA (LG2-MEL-205)CVCL_C5UB (LG2-MEL-206)CVCL_C5UC (LG2-MEL-207)
CVCL_C5VA (LG2-MEL-220)CVCL_C5UV (LG2-MEL-28)
Originate from same individual CVCL_C5U9 ! LG2-EBV
Sex of cell Male
Age at sampling 31Y
Category Cancer cell line
Publications

PubMed=2967757; DOI=10.1002/eji.1830180503
Gerard Degiovanni, Thierry Lahaye, Michel Herin, Philippe Hainaut, Thierry Boon;
Antigenic heterogeneity of a human melanoma tumor detected by autologous CTL clones.
Eur. J. Immunol. 18:671-676(1988)

PubMed=2209693; DOI=10.1002/eji.1830200835
Gerard Degiovanni, Philippe Hainaut, Thierry Lahaye, Patrick Weynants, Thierry Boon;
Antigens recognized on a melanoma cell line by autologous cytolytic T lymphocytes are also expressed on freshly collected tumor cells.
Eur. J. Immunol. 20:1865-1868(1990)

PubMed=8566071; DOI=10.1002/eji.1830260135
Vincent G. Brichard, Jean Herman, Aline Van Pel, Claude Wildmann, Beatrice Gaugler, Thomas Wolfel, Thierry Boon, Bernard Lethe;
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
Eur. J. Immunol. 26:224-230(1996)

PubMed=12747754
Nathalie Vigneron, Annie Ooms, Sandra Morel, Gerard Degiovanni, Benoit J. van den Eynde;
Identification of a new peptide recognized by autologous cytolytic T lymphocytes on a human melanoma.
Cancer Immun. 2:9.1-9.10(2002)

Cross-references
Encyclopedic resources Wikidata; Q116049684
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5