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Cellosaurus MZ2-MEL.43 (CVCL_C5U6)

[Text version]
Cell line name MZ2-MEL.43
Accession CVCL_C5U6
Resource Identification Initiative To cite this cell line use: MZ2-MEL.43 (RRID:CVCL_C5U6)
Comments Population: Caucasian.
Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5U4 (MZ2-MEL.3.0)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2529220; DOI=10.1002/ijc.2910440413
Benoit J. van den Eynde, Philippe Hainaut, Michel Herin, Alexander Knuth, Carine Lemoine, Patrick Weynants, Pierre van der Bruggen, Rene Fauchet, Thierry Boon;
Presence on a human melanoma of multiple antigens recognized by autologous CTL.
Int. J. Cancer 44:634-640(1989)

PubMed=8566071; DOI=10.1002/eji.1830260135
Vincent G. Brichard, Jean Herman, Aline Van Pel, Claude Wildmann, Beatrice Gaugler, Thomas Wolfel, Thierry Boon, Bernard Lethe;
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
Eur. J. Immunol. 26:224-230(1996)

PubMed=8642259; DOI=10.1084/jem.183.3.1173; PMCID=PMC2192325
Yannik Guilloux, Sophie Lucas, Vincent G. Brichard, Aline Van Pel, Christophe Viret, Etienne De Plaen, Francis Brasseur, Bernard Lethe, Francine Jotereau, Thierry Boon;
A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene.
J. Exp. Med. 183:1173-1183(1996)

Cross-references
Encyclopedic resources Wikidata; Q116049847
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5