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Cellosaurus Arbo (CVCL_C5U2)

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Cell line name Arbo
Accession CVCL_C5U2
Resource Identification Initiative To cite this cell line use: Arbo (RRID:CVCL_C5U2)
Comments Doubling time: 48 hours (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812).
Omics: Genomics; Whole exome sequencing.
Miscellaneous: STR profile from personal communication of Safa, Firas M.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Asp1853Asn (c.5557G>A); ClinVar=VCV000128458; Zygosity=Unspecified (PubMed=36467812).
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Asn1983Ser (c.5948A>G); Zygosity=Unspecified (PubMed=36467812).
  • Mutation; HGNC; HGNC:7882; NOTCH2; Simple; p.Arg2400Ter (c.7198C>T); ClinVar=VCV000518450; Zygosity=Unspecified (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu206Ter (c.617T>A); Zygosity=Unspecified (PubMed=36467812).
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814,15
D5S8189,11
D7S82012
D8S117910,15
D13S3178,13
D16S53910,11
D18S5117,18
D21S1128,32.2
FGA21,25
Penta D13,14
Penta E10,12
TH018,9
TPOX9,11
vWA16,17

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Publications

DOI=10.1158/1538-7445.AM2022-3160
Ishwarya Satyavarapu, Firas M. Safa, Terri Rasmussen, Nakhle S. Saba;
Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, ArBo.
Cancer Res. 82 Suppl. 12:3160-3160(2022)

PubMed=36467812; DOI=10.1002/jha2.580; PMCID=PMC9713070
Firas M. Safa, Terri Rasmussen, Patricia A. Lobelle-Rich, Stephanie Collier, Nicholas Milligan, John Schmeig, Janet Schmid, Carol Wiewiorowski, Denise Totaro, Theresa C. Brown, Ishwarya Satyavarapu ...Show all 16 authors... , Melody Badoo, Nathan Ungerleider, Erik K. Flemington, Hana Safah, Nakhle S. Saba; Show fewer authors
Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.
eJHaem 3:1326-1329(2022)

Cross-references
Encyclopedic resources Wikidata; Q116048524
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number6