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Cellosaurus Arbo (CVCL_C5U2)

[Text version]
Cell line name Arbo
Accession CVCL_C5U2
Resource Identification Initiative To cite this cell line use: Arbo (RRID:CVCL_C5U2)
Comments Doubling time: 48 hours (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812).
Omics: Genomics; Whole exome sequencing.
Miscellaneous: STR profile from personal communication of Safa, Firas M.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Asp1853Asn (c.5557G>A); ClinVar=VCV000128458; Zygosity=Unspecified (PubMed=36467812).
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Asn1983Ser (c.5948A>G); Zygosity=Unspecified (PubMed=36467812).
  • Mutation; HGNC; HGNC:7882; NOTCH2; Simple; p.Arg2400Ter (c.7198C>T); ClinVar=VCV000518450; Zygosity=Unspecified (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu206Ter (c.617T>A); Zygosity=Unspecified (PubMed=36467812).
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814,15
D5S8189,11
D7S82012
D8S117910,15
D13S3178,13
D16S53910,11
D18S5117,18
D21S1128,32.2
FGA21,25
Penta D13,14
Penta E10,12
TH018,9
TPOX9,11
vWA16,17

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Publications

DOI=10.1158/1538-7445.AM2022-3160
Satyavarapu I., Safa F.M., Rasmussen T., Saba N.S.
Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, ArBo.
Cancer Res. 82 Suppl. 12:3160-3160(2022)

PubMed=36467812; DOI=10.1002/jha2.580; PMCID=PMC9713070
Safa F.M., Rasmussen T., Lobelle-Rich P.A., Collier S., Milligan N., Schmeig J., Schmid J., Wiewiorowski C., Totaro D., Brown T.C., Satyavarapu I., Badoo M., Ungerleider N., Flemington E.K., Safah H., Saba N.S.
Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.
eJHaem 3:1326-1329(2022)

Cross-references
Encyclopedic resources Wikidata; Q116048524
Entry history
Entry creation15-Dec-2022
Last entry update10-Apr-2025
Version number6