Cell line name |
Arbo |
Accession |
CVCL_C5U2 |
Resource Identification Initiative |
To cite this cell line use: Arbo (RRID:CVCL_C5U2) |
Comments |
Doubling time: 48 hours (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812). Omics: Genomics; Whole exome sequencing. Miscellaneous: STR profile from personal communication of Safa, Firas M. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. |
Sequence variations |
- Mutation; HGNC; HGNC:795; ATM; Simple; p.Asp1853Asn (c.5557G>A); ClinVar=VCV000128458; Zygosity=Unspecified (PubMed=36467812).
- Mutation; HGNC; HGNC:795; ATM; Simple; p.Asn1983Ser (c.5948A>G); Zygosity=Unspecified (PubMed=36467812).
- Mutation; HGNC; HGNC:7882; NOTCH2; Simple; p.Arg2400Ter (c.7198C>T); ClinVar=VCV000518450; Zygosity=Unspecified (DOI=10.1158/1538-7445.AM2022-3160; PubMed=36467812).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu206Ter (c.617T>A); Zygosity=Unspecified (PubMed=36467812).
|
Disease |
Mantle cell lymphoma (NCIt: C4337) Mantle cell lymphoma (ORDO: Orphanet_52416) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Male |
Age at sampling |
69Y |
Category |
Cancer cell line |
STR profile |
Source(s): Direct_author_submission
Markers:Amelogenin | X,Y |
CSF1PO | 10,12 |
D3S1358 | 14,15 |
D5S818 | 9,11 |
D7S820 | 12 |
D8S1179 | 10,15 |
D13S317 | 8,13 |
D16S539 | 10,11 |
D18S51 | 17,18 |
D21S11 | 28,32.2 |
FGA | 21,25 |
Penta D | 13,14 |
Penta E | 10,12 |
TH01 | 8,9 |
TPOX | 9,11 |
vWA | 16,17 |
Run an STR similarity search on this cell line |
Publications | DOI=10.1158/1538-7445.AM2022-3160 Satyavarapu I., Safa F.M., Rasmussen T., Saba N.S. Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, ArBo. Cancer Res. 82 Suppl. 12:3160-3160(2022) PubMed=36467812; DOI=10.1002/jha2.580; PMCID=PMC9713070 Safa F.M., Rasmussen T., Lobelle-Rich P.A., Collier S., Milligan N., Schmeig J., Schmid J., Wiewiorowski C., Totaro D., Brown T.C., Satyavarapu I., Badoo M., Ungerleider N., Flemington E.K., Safah H., Saba N.S. Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo. eJHaem 3:1326-1329(2022) |
Cross-references |
Encyclopedic resources |
Wikidata; Q116048524
|
Entry history |
Entry creation | 15-Dec-2022 |
Last entry update | 10-Apr-2025 |
Version number | 6 |
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