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Cellosaurus STSW-01-LUC (CVCL_C5TY)

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Cell line name STSW-01-LUC
Accession CVCL_C5TY
Resource Identification Initiative To cite this cell line use: STSW-01-LUC (RRID:CVCL_C5TY)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Schwann cell; CL=CL_0002573.
Sequence variations
  • Gene deletion; HGNC; HGNC:7773; NF2; Zygosity=Heterozygous (PubMed=35732500).
  • Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Heterozygous (PubMed=35732500).
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Trp60Cysfs*62 (c.180delG); Zygosity=Heterozygous; Note=Germline (PubMed=35732500).
  • Mutation; HGNC; HGNC:11103; SMARCB1; Simple; p.Glu122Ter (c.364G>T); ClinVar=VCV001076272; Zygosity=Heterozygous; Note=Germline (PubMed=35732500).
Disease Schwannomatosis (NCIt: C6557)
Schwannomatosis (ORDO: Orphanet_93921)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5TX (STSW-01)
Sex of cell Sex unspecified
Age at sampling 32Y
Category Telomerase immortalized cell line
Publications

PubMed=35732500; DOI=10.1101/mcs.a006178; PMCID=PMC9235848
Abdulrahman Allaf, Berta Victoria, Rosa Rosario, Carly Misztal, Sakir Humayun Gultekin, Christine T. Dinh, Cristina Fernandez-Valle;
WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line.
Cold Spring Harb. Mol. Case Stud. 8:a006178.1-a006178.16(2022)

Cross-references
Encyclopedic resources Wikidata; Q116050579
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number7