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Cellosaurus Malpha2-3 (CVCL_C5GG)

[Text version]
Cell line name Malpha2-3
Accession CVCL_C5GG
Resource Identification Initiative To cite this cell line use: Malpha2-3 (RRID:CVCL_C5GG)
Comments Group: Animal toxin research hybridoma.
Characteristics: The mAb produced by this hybridoma partially mimicks the nicotinic AchR.
Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P01426; Naja pallida short neurotoxin 1 (Neurotoxin alpha) (Note=Reacts with short neurotoxins from many snake species).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma

PubMed=2430832; DOI=10.1016/0014-5793(86)81024-9
Tremeau O., Boulain J.-C., Couderc J., Fromageot P., Menez A.
A monoclonal antibody which recognized the functional site of snake neurotoxins and which neutralizes all short-chain variants.
FEBS Lett. 208:236-240(1986)

PubMed=9295323; DOI=10.1074/jbc.272.38.23775
Merienne K., Germain N., Zinn-Justin S., Boulain J.-C., Ducancel F., Menez A.
The functional architecture of an acetylcholine receptor-mimicking antibody.
J. Biol. Chem. 272:23775-23783(1997)

Encyclopedic resources Wikidata; Q116049767
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2