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Cellosaurus FM58 (CVCL_C595)

[Text version]
Cell line name FM58
Synonyms FM-58; FM 58
Accession CVCL_C595
Resource Identification Initiative To cite this cell line use: FM58 (RRID:CVCL_C595)
Comments Omics: Array-based CGH.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01
HLA-BB*07:02,15:01:01:01
HLA-CC*03:04,07:02
Class II
HLA-DPDPB1*02:01:02,04:01
HLA-DQDQB1*03:02,05:01
HLA-DRDRB1*10:01,04:01:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ECACC=13012414; ESTDAB=ESTDAB-018

Markers:
AmelogeninX,Y
CSF1PO11
D3S135816,17
D5S81811,12
D7S82010,11
D13S31712
D16S53912
FGA22
TH016
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=7656272; DOI=10.1007/BF01527402
Kirkin A.F., Petersen T.R., Olsen A.C., Li L., thor Straten P., Zeuthen J.
Generation of human-melanoma-specific T lymphocyte clones defining novel cytolytic targets with panels of newly established melanoma cell lines.
Cancer Immunol. Immunother. 41:71-81(1995)

PubMed=8968104
Bartkova J., Lukas J., Guldberg P., Alsner J., Kirkin A.F., Zeuthen J., Bartek J.
The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.
Cancer Res. 56:5475-5483(1996)

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M., Guldberg P., Borg A.
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line collections (Providers) ECACC; 13012414
Cell line databases/resources cancercelllines; CVCL_C595
ESTDAB; ESTDAB-018
Encyclopedic resources Wikidata; Q54835052
Gene expression databases GEO; GSM156046
Polymorphism and mutation databases Cosmic; 808555
Cosmic; 874440
Cosmic; 972265
Cosmic; 1006229
Cosmic; 1047669
Cosmic; 2163771
IARC_TP53; 26096
Progenetix; CVCL_C595
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number21