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Cellosaurus 624.28 Mel (CVCL_C586)

[Text version]
Cell line name 624.28 Mel
Synonyms 624.28-MEL; Mel-624.28; Me 624.28; 624.28; 624-28
Accession CVCL_C586
Resource Identification Initiative To cite this cell line use: 624.28 Mel (RRID:CVCL_C586)
Comments Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: Metastatic; Not specified.
HLA typing Source: PubMed=15592718
Class I
HLA-AA*11:01,03:01
HLA-BB*07:02,14:02
HLA-CC*08:02
Class II
HLA-DPDPB1*20:01,15:01
HLA-DQDQB1*03:01:01,02:01
HLA-DRDRB1*04:01:01,07:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8054 (624-mel)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-121

Markers:
AmelogeninX,Y
CSF1PO10
D3S135814,16
D5S81812
D7S82010,12
D13S31710,13
FGA24
TH019.3
TPOX8,10
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=9670966; DOI=10.4049/jimmunol.161.2.877
Maria P. Bettinotti, Christina J. Kim, Kang-Hun Lee, Matthew Roden, Janice N. Cormier, Monica C. Panelli, Kenneth K. Parker, Francesco M. Marincola;
Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy.
J. Immunol. 161:877-889(1998)

PubMed=10754339; DOI=10.4049/jimmunol.164.8.4382
Monica C. Panelli, Maria P. Bettinotti, Kate Lally, Galen Anthony Ohnmacht, Yong Li, Paul F. Robbins, Adam Riker, Steven A. Rosenberg, Francesco M. Marincola;
A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12.
J. Immunol. 164:4382-4392(2000)

PubMed=11924911; DOI=10.1097/00002371-200201000-00007; PMCID=PMC2424231
Stacy Eleanor Thurber, Hung T. Khong, Udai Shankar Kammula, Steven A. Rosenberg;
Identification of endogenous HLA-A2-restricted reactivity against shared melanoma antigens in patients using the quantitative real-time polymerase chain reaction.
J. Immunother. 25:63-71(2002)

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=18172304; DOI=10.1158/0008-5472.CAN-07-1939
Marianna Sabatino, Ying-Dong Zhao, Sonia Voiculescu, Alessandro Monaco, Paul F. Robbins, Laszlo Karai, Brian J. Nickoloff, Michele Maio, Silvia Selleri, Francesco M. Marincola, Ena Wang;
Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis.
Cancer Res. 68:122-131(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C586
ESTDAB; ESTDAB-121
Encyclopedic resources Wikidata; Q54604359
Gene expression databases GEO; GSM218053
GEO; GSM1092560
Polymorphism and mutation databases Progenetix; CVCL_C586
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number15