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Cellosaurus SV7tert PDGFtu1 (CVCL_C573)

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Cell line name SV7tert PDGFtu1
Synonyms SV7tert PDGF tumor-1
Accession CVCL_C573
Resource Identification Initiative To cite this cell line use: SV7tert PDGFtu1 (RRID:CVCL_C573)
Comments Characteristics: The parent cell line was implanted into nude mice and formed tumors from which the cell line was derived (PubMed=15695519).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8800; PDGFB.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Kidney angiomyolipoma (NCIt: C3888)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0F39 (SV7tert PDGF)
Sex of cell Female
Age at sampling 63Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-4008

Markers:
AmelogeninX
CSF1PO10,12
D2S133823,24
D3S135815,16
D5S81811,13
D7S82011
D8S117911,12
D13S3178
D16S5399,11
D18S5116
D19S43314,15
D21S1129
FGA21,24
Penta D8,13
Penta E7,23
TH016,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=15695519; DOI=10.1074/jbc.M500411200
Baskaran Govindarajan, Asha Shah, Cynthia Cohen, Rebecca S. Arnold, Jeffrey Scot Schechner, Jun Chung, Arthur M. Mercurio, Rhoda M. Alani, Byungwoo Ryu, Chun-Yang Fan, Jose Manuel Cuezva ...Show all 13 authors... , Marta Martinez, Jack Leonard Arbiser; Show fewer authors
Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
J. Biol. Chem. 280:13936-13943(2005)

Cross-references
Cell line collections (Providers) ATCC; CRL-4008
Encyclopedic resources Wikidata; Q54970987
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number19