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Cellosaurus RPMI-8322 (CVCL_C542)

[Text version]

Cell line name RPMI-8322
Synonyms RPMI 8322; RPMI8322; Roswell Park Memorial Institute 8322; M-5; M5
Accession CVCL_C542
Resource Identification Initiative To cite this cell line use: RPMI-8322 (RRID:CVCL_C542)
Comments Doubling time: 38 hours (PubMed=1127734).
Misspelling: RPMI8332; In Cosmic 1054846 and PubMed=17308088.
Disease Melanoma (NCIt: C3224)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C543 (RPMI8322/CDDP-300 )
Originate from same individual CVCL_ZY44 ! RPMI-7022
CVCL_LH91 ! RPMI-7711
CVCL_LH87 ! RPMI-7821
CVCL_T323 ! RPMI-8252
CVCL_U115 ! RPMI-8342
CVCL_X375 ! RPMI-8362
CVCL_X376 ! RPMI-8372
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line

PubMed=1127734; DOI=10.1093/jnci/54.5.1037
Liao S.-K., Dent P.B., McCulloch P.B.
Characterization of human maligant melanoma cell lines. I. Morphology and growth characteristics in culture.
J. Natl. Cancer Inst. 54:1037-1044(1975)

McCulloch P.B., Dent P.B., Hayes P.R., Liao S.-K.
Common and individually specific chromosomal characteristics of cultured human melanoma.
Cancer Res. 36:398-404(1976)

Quinn L.A., Woods L.K., Merrick S.B., Arabasz N.M., Moore G.E.
Cytogenetic analysis of twelve human malignant melanoma cell lines.
J. Natl. Cancer Inst. 59:301-307(1977)

Sharma B.
In vitro immunization against human tumor cells with tumor cell fractions.
Cancer Res. 37:4660-4668(1977)

PubMed=2423348; DOI=10.1016/0014-4827(86)90037-6
Trejdosiewicz L.K., Southgate J., Kemshead J.T., Hodges G.M.
Phenotypic analysis of cultured melanoma cells. Expression of cytokeratin-type intermediate filaments by the M5 human melanoma cell line.
Exp. Cell Res. 164:388-398(1986)

PubMed=1832891; DOI=10.1016/0277-5379(91)90277-K
Hansson J., Fichtinger-Schepman A.M.J., Edgren M.R., Ringborg U.
Comparative study of two human melanoma cell lines with different sensitivities to mustine and cisplatin.
Eur. J. Cancer 27:1039-1045(1991)

PubMed=8845476; DOI=10.1097/00001813-199510000-00005
Zhao R., Rabo Y.B., Egyhazi S., Andersson A., Edgren M.R., Linder S., Hansson J.
Apoptosis and c-jun induction by cisplatin in a human melanoma cell line and a drug-resistant daughter cell line.
Anticancer Drugs 6:657-668(1995)

PubMed=17308088; DOI=10.1158/0008-5472.CAN-06-3311
Shields J.M., Thomas N.E., Cregger M., Berger A.J., Leslie M., Torrice C., Hao H.-L., Penland S., Arbiser J.L., Scott G., Zhou T., Bar-Eli M., Bear J.E., Der C.J., Kaufmann W.K., Rimm D.L., Sharpless N.E.
Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma.
Cancer Res. 67:1502-1512(2007)

Anatomy/cell type resources BTO; BTO:0005710
Encyclopedic resources Wikidata; Q54951269
Polymorphism and mutation databases Cosmic; 1054846
Cosmic; 1507607
Cosmic; 2233667
Entry history
Entry creation22-Oct-2012
Last entry update29-Oct-2020
Version number15