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Cellosaurus RPMI-8322 (CVCL_C542)

[Text version]
Cell line name RPMI-8322
Synonyms RPMI 8322; RPMI8322; Roswell Park Memorial Institute 8322; M-5; M5
Accession CVCL_C542
Resource Identification Initiative To cite this cell line use: RPMI-8322 (RRID:CVCL_C542)
Comments Doubling time: 38 hours (PubMed=1127734).
Misspelling: RPMI8332; Cosmic=1054846; PubMed=17308088.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
HLA typing Source: PubMed=77569
Class I
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C543 (RPMI8322/CDDP-300)
Originate from same individual CVCL_ZY44 ! RPMI-7022
CVCL_LH91 ! RPMI-7711
CVCL_LH87 ! RPMI-7821
CVCL_T323 ! RPMI-8252
CVCL_U115 ! RPMI-8342
CVCL_X375 ! RPMI-8362
CVCL_X376 ! RPMI-8372
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line

PubMed=1127734; DOI=10.1093/jnci/54.5.1037
Liao S.-K., Dent P.B., McCulloch P.B.
Characterization of human maligant melanoma cell lines. I. Morphology and growth characteristics in culture.
J. Natl. Cancer Inst. 54:1037-1044(1975)

McCulloch P.B., Dent P.B., Hayes P.R., Liao S.-K.
Common and individually specific chromosomal characteristics of cultured human melanoma.
Cancer Res. 36:398-404(1976)

Quinn L.A., Woods L.K., Merrick S.B., Arabasz N.M., Moore G.E.
Cytogenetic analysis of twelve human malignant melanoma cell lines.
J. Natl. Cancer Inst. 59:301-307(1977)

Sharma B.
In vitro immunization against human tumor cells with tumor cell fractions.
Cancer Res. 37:4660-4668(1977)

PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x
Espmark J.A., Ahlqvist-Roth L., Sarne L., Persson A.
Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique.
Tissue Antigens 11:279-286(1978)

PubMed=2423348; DOI=10.1016/0014-4827(86)90037-6
Trejdosiewicz L.K., Southgate J., Kemshead J.T., Hodges G.M.
Phenotypic analysis of cultured melanoma cells. Expression of cytokeratin-type intermediate filaments by the M5 human melanoma cell line.
Exp. Cell Res. 164:388-398(1986)

PubMed=1832891; DOI=10.1016/0277-5379(91)90277-K
Hansson J., Fichtinger-Schepman A.M.J., Edgren M.R., Ringborg U.
Comparative study of two human melanoma cell lines with different sensitivities to mustine and cisplatin.
Eur. J. Cancer 27:1039-1045(1991)

PubMed=8845476; DOI=10.1097/00001813-199510000-00005
Zhao R., Rabo Y.B., Egyhazi Brage S., Andersson A., Edgren M.R., Linder S., Hansson J.
Apoptosis and c-jun induction by cisplatin in a human melanoma cell line and a drug-resistant daughter cell line.
Anticancer Drugs 6:657-668(1995)

PubMed=17308088; DOI=10.1158/0008-5472.CAN-06-3311
Shields J.M., Thomas N.E., Cregger M., Berger A.J., Leslie M., Torrice C., Hao H.-L., Penland S., Arbiser J.L., Scott G.A., Zhou T., Bar-Eli M., Bear J.E., Der C.J., Kaufmann W.K., Rimm D.L., Sharpless N.E.
Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma.
Cancer Res. 67:1502-1512(2007)

Anatomy/cell type resources BTO; BTO:0005710
Encyclopedic resources Wikidata; Q54951269
Polymorphism and mutation databases Cosmic; 1054846
Cosmic; 1507607
Cosmic; 2233667
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number17