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Cellosaurus Mel-NT3-00 (CVCL_C532)

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Cell line name Mel-NT3-00
Accession CVCL_C532
Resource Identification Initiative To cite this cell line use: Mel-NT3-00 (RRID:CVCL_C532)
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,68:01:02
HLA-BB*44:02:01:01,49:02
HLA-CC*06:02,07:04
Class II
HLA-DPDPB1*04:02,04:01
HLA-DQDQB1*03:01:01,02:01
HLA-DRDRB1*11:01:01,03:01:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-117

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815
D5S81811,12
D7S82010,12
D13S3178,12
FGA21,26
TH016
TPOX11,12
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C532
ESTDAB; ESTDAB-117
Encyclopedic resources Wikidata; Q54905121
Polymorphism and mutation databases Cosmic; 2163826
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number15