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Cellosaurus 2102EP (CVCL_C522)

[Text version]
Cell line name 2102EP
Synonyms 2102Ep; 2102 Ep; 2,102 Ep
Accession CVCL_C522
Resource Identification Initiative To cite this cell line use: 2102EP (RRID:CVCL_C522)
Comments Omics: Proteomics; Quantitative.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Testis; UBERON=UBERON_0000473.
Disease Embryonal carcinoma (NCIt: C3752)
Embryonal carcinoma (ORDO: Orphanet_180226)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C0QK (2102EP-R)CVCL_3037 (N2102Ep Clone 2/A6)CVCL_1Q49 (PC21A1)
Originate from same individual CVCL_C523 ! 2102ER
Sex of cell Male
Age at sampling 23Y
Category Cancer cell line
Publications

PubMed=6169654; DOI=10.1002/ijc.2910260304
Peter W. Andrews, David Leigh Bronson, Frances J. Benham, Sidney Strickland, Barbara B. Knowles;
A comparative study of eight cell lines derived from human testicular teratocarcinoma.
Int. J. Cancer 26:269-280(1980)

PubMed=7471097
Nancy Wang, Beth Trend, David Leigh Bronson, Elwin Eugene Fraley;
Nonrandom abnormalities in chromosome 1 in human testicular cancers.
Cancer Res. 40:796-802(1980)

PubMed=7095898; DOI=10.1002/ijc.2910290507
Peter W. Andrews, Peter Neville Goodfellow, Lynne Hamburger Shevinsky, David Leigh Bronson, Barbara B. Knowles;
Cell-surface antigens of a clonal human embryonal carcinoma cell line: morphological and antigenic differentiation in culture.
Int. J. Cancer 29:523-531(1982)

PubMed=17284651; DOI=10.1634/stemcells.2006-0236
Richard Josephson, Carol J. Ording, Ying Liu, Soojung Shin, Uma Lakshmipathy, Arazdordi Toumadje, Bradley Love, Jonathan D. Chesnut, Peter W. Andrews, Mahendra Surendra Rao, Jonathan M. Auerbach;
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research.
Stem Cells 25:437-446(2007)

PubMed=20428235; DOI=10.1371/journal.pone.0010263; PMCID=PMC2859053
Outi Hovatta, Marisa Elisabetta Elena Jaconi Devaud, Virpi Tohonen, Frederique Sloan-Bena, Stefania Gimelli, Alexis Gina Bosman, Frida Holm, Stefan Wyder, Evgeny M. Zdobnov, Olivier Irion, Peter W. Andrews ...Show all 15 authors... , Stylianos E. Antonarakis, Marco Zucchelli, Juha Kere, Anis Feki; Show fewer authors
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes.
PLoS ONE 5:e10263.1-e10263.10(2010)

PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868
Darren R. Feldman, Gopa Iyer, Lindsay Van Alstine, Sujata Patil, Hikmat Al-Ahmadie, Victor E. Reuter, George J. Bosl, Raju S.K. Chaganti, David B. Solit;
Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.
Clin. Cancer Res. 20:3712-3720(2014)

PubMed=35084545; DOI=10.1007/s00345-022-03936-1; PMCID=PMC8921118
Alexander Fichtner, Hanibal Bohnenberger, Omar Elakad, Annika Richter, Christof Lenz, Christoph Oing, Philipp Strobel, Stefan Kueffer, Daniel Nettersheim, Felix Bremmer;
Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry.
World J. Urol. 40:373-383(2022)

Cross-references
Anatomy/cell type resources BTO; BTO_0005287
Encyclopedic resources Wikidata; Q54583213
Experimental variables resources EFO; EFO_0002957
Polymorphism and mutation databases Cosmic; 2077185
Cosmic; 2163762
Proteomic databases PRIDE; PXD030251
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number19