Cellosaurus cell line FS7-20.12 (CVCL

Cellosaurus FS7-20.12 (CVCL_C4TW)

Cross-references
Cell line name	FS7-20.12
Accession	CVCL_C4TW
Resource Identification Initiative	To cite this cell line use: FS7-20.12 (RRID:CVCL_C4TW)
Comments	Characteristics: T-cell hybridoma. Produces IL2, IL10, IFNG, macrophage-activating factor (MAF) and Ia induction factor (IaIF) when stimulated by concanavalin A (ConA). Compared to the parent cell line, produces relatively high level of IL2 and undectable quantity of the four other lymphokines (PubMed=6223094).
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_C4TV (FS7-20)
Category	Hybridoma
Publications	PubMed=6223094; DOI=10.4049/jimmunol.131.2.794 Albert Zlotnik, Walden K. Roberts, Adriana Vasil, Elliott Blumenthal, Francisco Larosa, H. James Leibson, Robert O. Endres, Sam D. Graham Jr., Janice White, Jeffrey Hill, Peter M. Henson ...Show all 15 authors... , John R. Klein, Michael John Bevan, Philippa Marrack, John Wayne Kappler; Show fewer authors Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine? J. Immunol. 131:794-800(1983) PubMed=6197379; DOI=10.1128/IAI.43.1.380-385.1984; PMCID=PMC263437 Betty An-Ye Wu-Hsieh, Albert Zlotnik, Dexter H. Howard; T-cell hybridoma-produced lymphokine that activates macrophages to suppress intracellular growth of Histoplasma capsulatum. Infect. Immun. 43:380-385(1984)
Encyclopedic resources	Wikidata; Q116049042
Entry history
Entry creation	15-Dec-2022
Last entry update	21-Mar-2023
Version number	2