| Comments |
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Basophil progenitor cell; CL=CL_0000613. |
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| Sequence variations |
- Mutation; HGNC; HGNC:76; ABL1; Simple; p.Glu450Gln (c.1348G>C); Zygosity=Unspecified; Note=Acquired during resistance selection process (PubMed=21718141).
- Mutation; HGNC; HGNC:76; ABL1; Simple; p.Glu459Lys (c.1375G>A); Zygosity=Unspecified; Note=Acquired during resistance selection process (PubMed=21718141).
- Mutation; HGNC; HGNC:76; ABL1; Simple; p.Glu470Lys (c.1408G>A); Zygosity=Unspecified; Note=Acquired during resistance selection process (PubMed=21718141).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Arg (c.395A>G); ClinVar=VCV000376625; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0379 (Ku812) |
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| Sex of cell |
Male |
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| Age at sampling |
38Y |
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| Category |
Cancer cell line |
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| Entry history |
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| Entry creation | 10-Apr-2025 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 1 |
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