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Cellosaurus MGN3-1 (CVCL_C4PL)

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Cell line name MGN3-1
Synonyms Mouse GhreliNoma 3-1
Accession CVCL_C4PL
Resource Identification Initiative To cite this cell line use: MGN3-1 (RRID:CVCL_C4PL)
Comments Characteristics: Secretes substantial amount of ghrelin.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Disease Mouse gastric neuroendocrine neoplasm (NCIt: C24219)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: GP-Tag transgenic.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=20375182; DOI=10.1210/en.2010-0090
Hiroshi Iwakura, Yu-Shu Li, Hiroyuki Ariyasu, Hiroshi Hosoda, Naotetsu Kanamoto, Mika Bando, Go Yamada, Kiminori Hosoda, Kazuwa Nakao, Kenji Kangawa, Takashi Akamizu;
Establishment of a novel ghrelin-producing cell line.
Endocrinology 151:2940-2945(2010)

PubMed=21521750; DOI=10.1210/en.2010-1455
Hiroshi Iwakura, Hiroyuki Ariyasu, Hiroshi Hosoda, Go Yamada, Kiminori Hosoda, Kazuwa Nakao, Kenji Kangawa, Takashi Akamizu;
Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line, MGN3-1 in vitro.
Endocrinology 152:2619-2625(2011)

Cross-references
Encyclopedic resources Wikidata; Q116049783
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number5