Cellosaurus cell line NT-38 (CVCL

Cross-references
Cell line name	NT-38
Accession	CVCL_C4N9
Resource Identification Initiative	To cite this cell line use: NT-38 (RRID:CVCL_C4N9)
Comments	Doubling time: 5.21 days (PubMed=36269546). Derived from site: In situ; Small intestine, duodenum; UBERON=UBERON_0002114.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1346Ter (c.4037C>A); ClinVar=VCV001737245; Zygosity=Unspecified (PubMed=36269546). Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser259Phe (c.776C>T); ClinVar=VCV000040603; Zygosity=Unspecified (PubMed=36269546).
Disease	Duodenal neuroendocrine tumor (NCIt: C135080) Duodenal neuroendocrine tumor (ORDO: Orphanet_100076)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	78Y
Category	Cancer cell line
Publications	PubMed=36269546; DOI=10.1007/s13402-022-00727-z; PMCID=PMC9747820 Fabrice Viol, Bence Sipos, Martina Fahl, Till Sebastian Clauditz, Tania Amin, Malte Kriegs, Maike Nieser, Jakob Robert Izbicki, Samuel Huber, Ansgar W. Lohse, Jorg Schrader; Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy. Cell. Oncol. (Dordr.) 45:1401-1419(2022)
Cell line databases/resources	cancercelllines; CVCL_C4N9
Encyclopedic resources	Wikidata; Q116050018
Entry history
Entry creation	15-Dec-2022
Last entry update	19-Dec-2024
Version number	5