Cellosaurus cell line NT-38 (CVCL

Cross-references
Cell line name	NT-38
Accession	CVCL_C4N9
Resource Identification Initiative	To cite this cell line use: NT-38 (RRID:CVCL_C4N9)
Comments	Doubling time: 5.21 days (PubMed=36269546). Derived from site: In situ; Small intestine, duodenum; UBERON=UBERON_0002114.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1346Ter (c.4037C>A); ClinVar=VCV001737245; Zygosity=Unspecified (PubMed=36269546). Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser259Phe (c.776C>T); ClinVar=VCV000040603; Zygosity=Unspecified (PubMed=36269546).
Disease	Duodenal neuroendocrine tumor (NCIt: C135080) Duodenal neuroendocrine tumor (ORDO: Orphanet_100076)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	78Y
Category	Cancer cell line
Publications	PubMed=36269546; DOI=10.1007/s13402-022-00727-z; PMCID=PMC9747820 Viol F., Sipos B., Fahl M., Clauditz T.S., Amin T., Kriegs M., Nieser M., Izbicki J.R., Huber S., Lohse A.W., Schrader J. Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy. Cell. Oncol. (Dordr.) 45:1401-1419(2022)
Cell line databases/resources	cancercelllines; CVCL_C4N9
Encyclopedic resources	Wikidata; Q116050018
Entry history
Entry creation	15-Dec-2022
Last entry update	19-Dec-2024
Version number	5