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Cellosaurus LL2 (CVCL_C4MM)

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Cell line name LL2
Synonyms EPB-2; EPB2
Accession CVCL_C4MM
Resource Identification Initiative To cite this cell line use: LL2 (RRID:CVCL_C4MM)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma when labelled with the radioactive isotope technetium-99m is known as bectumomab (LymphoScan) and is used to detect non-Hodgkin's lymphoma.
Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P20273; Human CD22.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=2663143
Elizabeth J. Pawlak-Byczkowska, Hans J. Hansen, Arnold S. Dion, David M. Goldenberg;
Two new monoclonal antibodies, EPB-1 and EPB-2, reactive with human lymphoma.
Cancer Res. 49:4568-4577(1989)

PubMed=7691407; DOI=10.1007/BF01518451; PMCID=PMC11038067
Rhona Stein, Elizabeth Belisle, Hans J. Hansen, David M. Goldenberg;
Epitope specificity of the anti-(B cell lymphoma) monoclonal antibody, LL2.
Cancer Immunol. Immunother. 37:293-298(1993)

PubMed=7737671; DOI=10.1089/hyb.1994.13.469
Shui-On Leung, Jerry Shevitz, Matthew C. Pellegrini, Arnold S. Dion, Lisa B. Shih, David M. Goldenberg, Hans J. Hansen;
Chimerization of LL2, a rapidly internalizing antibody specific for B cell lymphoma.
Hybridoma 13:469-476(1994)

Cross-references
Biological sample resources ABCD; ABCD_AE447
Encyclopedic resources Wikidata; Q116049710
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2