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Cellosaurus WEHI-231-bcl-xL clone 3 (CVCL_C4M1)

[Text version]
Cell line name WEHI-231-bcl-xL clone 3
Synonyms WEHI-231-Clone 3; WEHI-231 Clone 3
Accession CVCL_C4M1
Resource Identification Initiative To cite this cell line use: WEHI-231-bcl-xL clone 3 (RRID:CVCL_C4M1)
Comments Doubling time: 14.6 +- 1.2 hours (PubMed=7561089).
Genetic integration: Method=Transfection; Gene=MGI; MGI:88139; Bcl2l1 (Note=Isoform Bcl-xL; with a N-terminal FLAG tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c x NZB.
Hierarchy Parent: CVCL_0577 (WEHI-231)
Category Cancer cell line
Publications

PubMed=7561089; DOI=10.4049/jimmunol.155.8.3830
Merino R., Grillot D.A.M., Simonian P.L., Muthukkumar S., Fanslow W.C., Bondada S., Nunez G.
Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction.
J. Immunol. 155:3830-3838(1995)

Cross-references
Encyclopedic resources Wikidata; Q116050791
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number4