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Cellosaurus S5C4 (CVCL_C4LG)

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Cell line name S5C4
Accession CVCL_C4LG
Resource Identification Initiative To cite this cell line use: S5C4 (RRID:CVCL_C4LG)
Comments Doubling time: ~40 hours (PubMed=9870527).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: Ad2-Ad5 hybrid E1A 12S.
Derived from site: In situ; Brain, endothelium; UBERON=UBERON_0013694.
Cell type: Brain microvascular endothelial cell; CL=CL_2000044.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1.
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=9870527; DOI=10.1007/s11626-998-0032-y
John A. Wijsman, Richard R. Shivers;
Immortalized mouse brain endothelial cells are ultrastructurally similar to endothelial cells and respond to astrocyte-conditioned medium.
In Vitro Cell. Dev. Biol. Anim. 34:777-784(1998)

PubMed=12958429; DOI=10.1385/1-59259-419-0:307
Andreas Reichel, David J. Begley, N. Joan Abbott;
An overview of in vitro techniques for blood-brain barrier studies.
Methods Mol. Med. 89:307-324(2003)

Cross-references
Encyclopedic resources Wikidata; Q116050201
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number5