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Cellosaurus BBEC-SV (CVCL_C4L6)

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Cell line name BBEC-SV
Synonyms Bovine Brain Endothelial cells-SV40 transformed
Accession CVCL_C4L6
Resource Identification Initiative To cite this cell line use: BBEC-SV (RRID:CVCL_C4L6)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brain, capillary; UBERON=UBERON_8480001.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=9156338; DOI=10.1007/s11626-997-0042-1
Monique F. Stins, Nemani V. Prasadarao, Jin Zhou, Moshe Arditi, Kwang Sik Kim;
Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: development of an immortalized cell line to study pathophysiology of CNS disease.
In Vitro Cell. Dev. Biol. Anim. 33:243-247(1997)

PubMed=12958429; DOI=10.1385/1-59259-419-0:307
Andreas Reichel, David J. Begley, N. Joan Abbott;
An overview of in vitro techniques for blood-brain barrier studies.
Methods Mol. Med. 89:307-324(2003)

Cross-references
Encyclopedic resources Wikidata; Q116048565
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number5