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Cellosaurus alpha T2 line 4 (CVCL_C4KS)

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Cell line name alpha T2 line 4
Synonyms alphaT2 line 4
Accession CVCL_C4KS
Resource Identification Initiative To cite this cell line use: alpha T2 line 4 (RRID:CVCL_C4KS)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Eye, ocular lens, epithelium; UBERON=UBERON_0001803.
Cell type: Epithelial cell of ocular lens; CL=CL_0002224.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Cryaa-TAg transgenic.
Hierarchy Children:
CVCL_AW08 (alphaTN4)
Sex of cell Sex unspecified
Age at sampling 2M
Category Transformed cell line
Publications

PubMed=2562221
Takafumi Nakamura, Kathleen A. Mahon, Ruth Miskin, Anup Dey, Toichiro Kuwabara, Heiner Westphal;
Differentiation and oncogenesis: phenotypically distinct lens tumors in transgenic mice.
New Biol. 1:193-204(1989)

PubMed=1694016; DOI=10.1128/mcb.10.7.3700-3708.1990; PMCID=PMC360816
Takafumi Nakamura, David M. Donovan, Kazushige Hamada, Christina M. Sax, Barbara Norman, James R. Flanagan, Keiko Ozato, Heiner Westphal, Joram Piatigorsky;
Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes.
Mol. Cell. Biol. 10:3700-3708(1990)

Cross-references
Encyclopedic resources Wikidata; Q116048506
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number6