Cellosaurus cell line UMB1949 (CVCL

Cellosaurus UMB1949 (CVCL_C471)

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Cell line name

UMB1949

Synonyms

UMBSVtel

Accession

CVCL_C471

Resource Identification Initiative

To cite this cell line use: UMB1949 (RRID:CVCL_C471)

Comments

Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:12363; TSC2; Simple; p.Val1362Leufs*50 (c.4083_4087delAGTCG); ClinVar=VCV000049741; Zygosity=Unspecified (PubMed=17592550).

Disease

Kidney angiomyolipoma (NCIt: C3888)
Tuberous sclerosis 2 (NCIt: C75331)
Tuberous sclerosis complex (ORDO: Orphanet_805)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

36Y

Category

Transformed cell line

STR profile

Source(s): ATCC=CRL-4004

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D2S1338	17,19
D3S1358	15,18
D5S818	11
D7S820	9,10
D8S1179	13,14
D13S317	12,13
D16S539	12
D18S51	16,17
D19S433	14
D21S11	28,30
FGA	23
Penta D	10,13
Penta E	5,7
TH01	6,8
TPOX	12
vWA	18

Publications

PubMed=17592550; DOI=10.2119/2006-00070.Lim; PMCID=PMC1892760
So Dug Lim, William B. Stallcup, Benjamin Lefkove, Baskaran Govindarajan, Kit Sing Au, Hope Northrup, Deborah Lang, David Erich Fisher, Avani Patel, Mahul B. Amin, Jack Leonard Arbiser;
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Mol. Med. 13:160-165(2007)

Cross-references

Cell line collections (Providers)

ATCC; CRL-4004

Biological sample resources

BioSample; SAMN03471715

Encyclopedic resources

Wikidata; Q54991071

Entry history

Entry creation

22-Oct-2012

Last entry update

14-Aug-2025

Version number