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Cellosaurus CP-C (CVCL_C453)

[Text version]
Cell line name CP-C
Synonyms CP-C hTRT; CP-94251 hTERT
Accession CVCL_C453
Resource Identification Initiative To cite this cell line use: CP-C (RRID:CVCL_C453)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Cell type: Epithelial cell of esophagus; CL=CL_0002252.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (from parent cell line).
Disease Barrett esophagus (NCIt: C2891)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8WF (CP-94251)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-4029

Markers:
AmelogeninX,Y
CSF1PO9,13
D2S133817,21
D3S135816,18
D5S81812
D7S8208,11
D8S117910,12
D13S3178,10
D16S53911,12
D18S5112,17
D19S43312,14
D21S1131.2
FGA19,21
Penta D12
Penta E10,11
TH018,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=12807723; DOI=10.1093/carcin/bgg076; PMCID=PMC1559990
Maria Corinna A. Palanca-Wessels, Aloysius J. Klingelhutz, Brian J. Reid, Thomas H. Norwood, Kent E. Opheim, Thomas G. Paulson, Zi-Ding Feng, Peter S. Rabinovitch;
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
Carcinogenesis 24:1183-1190(2003)

Cross-references
Cell line collections (Providers) ATCC; CRL-4029
Encyclopedic resources Wikidata; Q54814364
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number15