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Cellosaurus SV-BEC (CVCL_C3X9)

[Text version]
Cell line name SV-BEC
Synonyms SV40 transformed-Bovine Endothelial Cells
Accession CVCL_C3X9
Resource Identification Initiative To cite this cell line use: SV-BEC (RRID:CVCL_C3X9)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-1143.
Doubling time: ~12 hours (PubMed=1683665).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Brain, capillary; UBERON=UBERON_8480001.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1683665; DOI=10.1007/BF02631242
Durieu-Trautmann O., Chaverot N., Perdomo J.J., Gounon P., Strosberg A.D., Couraud P.-O.
Immortalization of brain capillary endothelial cells with maintenance of structural characteristics of the blood-brain barrier endothelium.
In Vitro Cell. Dev. Biol. Anim. 27:771-778(1991)

Patent=WO1993006222A1
Claire M., Couraud P.-O., Durieu-Trautmann O., Chaverot N., Roux F., Strosberg A.D.
Immortalized cerebral endothelial cell lines, process for their preparation and applications thereof as a model for the study of cerebral physiopathology.
Patent number WO1993006222A1, 01-Apr-1993

PubMed=12958429; DOI=10.1385/1-59259-419-0:307
Reichel A., Begley D.J., Abbott N.J.
An overview of in vitro techniques for blood-brain barrier studies.
Methods Mol. Med. 89:307-324(2003)

Cross-references
Encyclopedic resources Wikidata; Q116050590
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number5