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Cellosaurus FB5 (CVCL_C3VU)

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Cell line name FB5
Accession CVCL_C3VU
Resource Identification Initiative To cite this cell line use: FB5 (RRID:CVCL_C3VU)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized ontuxizumab (MORAb-004) therapeutic antibody which was used in clinical trials for the treatment of metastatic melanoma.
Monoclonal antibody isotype: IgG2a.
Monoclonal antibody target: UniProtKB; Q9HCU0; Human CD248.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=1438285; DOI=10.1073/pnas.89.22.10832; PMCID=PMC50436
Wolfgang J. Rettig, Pilar Garin-Chesa, John Henry Healey, Sai L. Su, Eric A. Jaffe, Lloyd John Old;
Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 89:10832-10836(1992)

Cross-references
Encyclopedic resources Wikidata; Q116048976
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2