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Cellosaurus PK15S1-CD163 (CVCL_C3VN)

[Text version]
Cell line name PK15S1-CD163
Synonyms PK15(S1-CD163); PK15Sn-CD163
Accession CVCL_C3VN
Resource Identification Initiative To cite this cell line use: PK15S1-CD163 (RRID:CVCL_C3VN)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome (PRRSV).
Transfected with: VGNC; 108736; Pig SIGLEC1.
Transfected with: UniProtKB; E1AQW7; Pig CD163.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire.
Hierarchy Parent: CVCL_C3VM (PK15S1)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=30021620; DOI=10.1186/s13567-018-0569-z
Xie J.-X., Christiaens I., Yang B., Trus I., Devriendt B., Cui T.-T., Wei R.-F., Nauwynck H.J.
Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15(S1-CD163) and PK15(S10-CD163) cells.
Vet. Res. 49:67.1-67.13(2018)

PubMed=34205087; DOI=10.3390/vaccines9060594
Xie J.-X., Vereecke N., Theuns S., Oh D.-Y., Vanderheijden N., Trus I., Sauer J., Vyt P., Bonckaert C., Lalonde C., Provost C., Gagnon C.A., Nauwynck H.J.
Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus.
Vaccines (Basel) 9:594.1-594.13(2021)

Encyclopedic resources Wikidata; Q116050121
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3