Cellosaurus logo
expasy logo

Cellosaurus PK15S1-CD163 (CVCL_C3VN)

[Text version]
Cell line name PK15S1-CD163
Synonyms PK15(S1-CD163); PK15Sn-CD163
Accession CVCL_C3VN
Resource Identification Initiative To cite this cell line use: PK15S1-CD163 (RRID:CVCL_C3VN)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome (PRRSV).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Genetic integration: Method=Transfection/transduction; Gene=VGNC; VGNC:112737; Pig CD163.
Genetic integration: Method=Transfection/transduction; Gene=VGNC; VGNC:108736; Pig SIGLEC1.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire; VBO=VBO_0001146.
Hierarchy Parent: CVCL_C3VM (PK15S1)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=30021620; DOI=10.1186/s13567-018-0569-z; PMCID=PMC6052533
Jie-Xiong Xie, Isaura Christiaens, Bo Yang, Ivan Trus, Bert Devriendt, Ting-Ting Cui, Rui-Fang Wei, Hans J. Nauwynck;
Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15(S1-CD163) and PK15(S10-CD163) cells.
Vet. Res. 49:67.1-67.13(2018)

PubMed=34205087; DOI=10.3390/vaccines9060594; PMCID=PMC8229515
Jie-Xiong Xie, Nick Vereecke, Sebastiaan Theuns, Da-Young Oh, Nathalie Vanderheijden, Ivan Trus, Jannes Sauer, Philip Vyt, Caroline Bonckaert, Christian Lalonde, Chantale Provost ...Show all 13 authors... , Carl A. Gagnon, Hans J. Nauwynck; Show fewer authors
Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus.
Vaccines (Basel) 9:594.1-594.13(2021)

Cross-references
Encyclopedic resources Wikidata; Q116050121
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number7