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Cellosaurus HEK-Blue hACE2-TMPRSS2 (CVCL_C3S5)

[Text version]
Cell line name HEK-Blue hACE2-TMPRSS2
Accession CVCL_C3S5
Resource Identification Initiative To cite this cell line use: HEK-Blue hACE2-TMPRSS2 (RRID:CVCL_C3S5)
Comments Group: SARS-CoV-2 research cell line.
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB and AP-1-binding sites.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 439; ALPP.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 13557; ACE2.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11876; TMPRSS2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A7YK (HEK-Blue hACE2)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/hek-blue-hace2-tmprss2-cells
Cross-references
Encyclopedic resources Wikidata; Q116049297
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number5