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Cellosaurus RKC2 (CVCL_C3NK)

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Cell line name RKC2
Synonyms RKC-2; Rat Kupffer Cell line 2
Accession CVCL_C3NK
Resource Identification Initiative To cite this cell line use: RKC2 (RRID:CVCL_C3NK)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Kupffer cell; CL=CL_0000091.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Hierarchy Parent: CVCL_C3NJ (RKC1)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=17502155; DOI=10.1016/j.cyto.2007.03.003
Yan-Hua Peng, Michel M. Murr;
Establishment of immortalized rat Kupffer cell lines.
Cytokine 37:185-191(2007)

PubMed=28871174; DOI=10.1038/s41598-017-11082-7; PMCID=PMC5583293
Dafna Gilboa, Yasmin Haim-Ohana, Naamit Deshet-Unger, Nathalie Ben-Califa, Sahar Hiram-Bab, Debby Reuveni, Ehud Zigmond, Max Gassmann, Yankel Gabet, Chen Varol, Drorit Neumann;
Erythropoietin enhances Kupffer cell number and activity in the challenged liver.
Sci. Rep. 7:10379.1-10379.13(2017)

Cross-references
Encyclopedic resources Wikidata; Q116050179
Entry history
Entry creation15-Dec-2022
Last entry update14-Aug-2025
Version number6