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Cellosaurus PC3/DX/AR+ (CVCL_C3M6)

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Cell line name PC3/DX/AR+
Accession CVCL_C3M6
Resource Identification Initiative To cite this cell line use: PC3/DX/AR+ (RRID:CVCL_C3M6)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:644; AR.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3M5 (PC3/DX)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

DOI=10.29228/jrp.195
Hilal Acidereli, Ozge Cevik;
Investigation of the effects of bicalutamide and TRAIL signaling mechanism on docetaxel resistant prostate cancer cells.
J. Res. Pharm. 26:980-991(2022)

Cross-references
Encyclopedic resources Wikidata; Q116050112
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5