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Cellosaurus MVX-2 (CVCL_C3LY)

[Text version]
Cell line name MVX-2
Synonyms MaxiVaX-2; huGM-CSF clone 61.27; Clone #61.27
Accession CVCL_C3LY
Resource Identification Initiative To cite this cell line use: MVX-2 (RRID:CVCL_C3LY)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Culture Collection of Switzerland (CCOS); CCOS-1901.
Characteristics: Expression of CSF2 is under the control of a PGK promoter (PubMed=36092361).
Doubling time: 37 hours (Direct_author_submission).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2434; CSF2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Miscellaneous: Cell line name and doubling time from personal communication of Lathuiliere, Aurelien.
Derived from site: In situ; Muscle, semitendinosus; UBERON=UBERON_0001375.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3LX (IHM-2)
Sex of cell Female
Age at sampling 32Y
Category Telomerase immortalized cell line
Publications

Patent=US20220265727
Aurelien Lathuiliere, Nicolas Mach, Patrick Salmon;
Immortalized myoblast cell lines and uses thereof.
Patent number US20220265727, 25-Aug-2022

PubMed=36092361; DOI=10.1016/j.omtm.2022.07.017; PMCID=PMC9418741
Aurelien Lathuiliere, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Marie-Claude Belkouch, Valentin Saingier, Thomas Bouvarel, Davy Guillarme, Adrien Engel, Patrick Salmon ...Show all 14 authors... , Thomas Laumonier, Julien Grogg, Nicolas Mach; Show fewer authors
Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology.
Mol. Ther. Methods Clin. Dev. 26:441-458(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049838
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5