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Cellosaurus A549 MIR1343 KO (CVCL_C3IT)

[Text version]
Cell line name A549 MIR1343 KO
Synonyms miR-1343Delta A549
Accession CVCL_C3IT
Resource Identification Initiative To cite this cell line use: A549 MIR1343 KO (RRID:CVCL_C3IT)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 41902; MIR1343.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=29022142; DOI=10.1007/s00441-017-2697-6
Stolzenburg L.R., Harris A.
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis.
Cell Tissue Res. 371:325-338(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C3IT
Encyclopedic resources Wikidata; Q114310528
Gene expression databases GEO; GSM2635908
GEO; GSM2635910
GEO; GSM2635913
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5