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Cellosaurus IPS(IMR90)-4-CHMP1A KO (CVCL_C3HI)

[Text version]
Cell line name IPS(IMR90)-4-CHMP1A KO
Synonyms CHMP1A null iPSC; iPSC_CHMP1A_null
Accession CVCL_C3HI
Resource Identification Initiative To cite this cell line use: IPS(IMR90)-4-CHMP1A KO (RRID:CVCL_C3HI)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8740; CHMP1A.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C437 (IPS(IMR90)-4)
Sex of cell Female
Age at sampling 16FW
Category Induced pluripotent stem cell
Publications

PubMed=30044992; DOI=10.1016/j.celrep.2018.06.100; PMCID=PMC6178983
Coulter M.E., Dorobantu C.M., Lodewijk G.A., Delalande F., Cianferani S., Ganesh V.S., Smith R.S., Lim E.T.-T., Xu C.S., Pang S., Wong E.T., Lidov H.G.W., Calicchio M.L., Yang E., Gonzalez D.M., Schlaeger T.M., Mochida G.H., Hess H., Lee W.-C.A., Lehtinen M.K., Kirchhausen T.L., Haussler D., Jacobs F.M.J., Gaudin R., Walsh C.A.
The ESCRT-III protein CHMP1A mediates secretion of sonic hedgehog on a distinctive subtype of extracellular vesicles.
Cell Rep. 24:973-986.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q114311752
Gene expression databases GEO; GSM3192178
GEO; GSM3192179
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7