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Cellosaurus IPS(IMR90)-4-CHMP1A KO (CVCL_C3HI)

[Text version]
Cell line name IPS(IMR90)-4-CHMP1A KO
Synonyms CHMP1A null iPSC; iPSC_CHMP1A_null
Accession CVCL_C3HI
Resource Identification Initiative To cite this cell line use: IPS(IMR90)-4-CHMP1A KO (RRID:CVCL_C3HI)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 8740; CHMP1A.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C437 (IPS(IMR90)-4)
Sex of cell Female
Age at sampling 16FW
Category Induced pluripotent stem cell

PubMed=30044992; DOI=10.1016/j.celrep.2018.06.100
Coulter M.E., Dorobantu C.M., Lodewijk G.A., Delalande F., Cianferani S., Ganesh V.S., Smith R.S., Lim E.T., Xu C.S., Pang S., Wong E.T., Lidov H.G.W., Calicchio M.L., Yang E., Gonzalez D.M., Schlaeger T.M., Mochida G.H., Hess H., Lee W.-C.A., Lehtinen M.K., Kirchhausen T.L., Haussler D., Jacobs F.M.J., Gaudin R., Walsh C.A.
The ESCRT-III protein CHMP1A mediates secretion of sonic hedgehog on a distinctive subtype of extracellular vesicles.
Cell Rep. 24:973-986.e8(2018)

Encyclopedic resources Wikidata; Q114311752
Gene expression databases GEO; GSM3192178
GEO; GSM3192179
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5