Cellosaurus cell line IPS(IMR90)-4-CHMP1A KO (CVCL

Cellosaurus IPS(IMR90)-4-CHMP1A KO (CVCL_C3HI)

Cross-references
Cell line name	IPS(IMR90)-4-CHMP1A KO
Synonyms	CHMP1A null iPSC; iPSC_CHMP1A_null
Accession	CVCL_C3HI
Resource Identification Initiative	To cite this cell line use: IPS(IMR90)-4-CHMP1A KO (RRID:CVCL_C3HI)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8740; CHMP1A. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Fetal lung; UBERON=UBERON_0005597. Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_C437 (IPS(IMR90)-4)
Sex of cell	Female
Age at sampling	16FW
Category	Induced pluripotent stem cell
Publications	PubMed=30044992; DOI=10.1016/j.celrep.2018.06.100; PMCID=PMC6178983 Michael Edward Coulter, Cristina M. Dorobantu, Gerrald A. Lodewijk, Francois Delalande, Sarah Cianferani, Vijay S. Ganesh, Richard S. Smith, Elaine Teng-Tim Lim, C. Shan Xu, Song Pang, Eric T. Wong ...Show all 25 authors... , Hart G.W. Lidov, Monica L. Calicchio, Edward Yang, Dilenny M. Gonzalez, Thorsten M. Schlaeger, Ganeshwaran H. Mochida, Harald Hess, Wei-Chung Allen Lee, Maria K. Lehtinen, Tomas Leopold Kirchhausen, David Haussler, Frank M.J. Jacobs, Raphael Gaudin, Christopher A. Walsh; Show fewer authors The ESCRT-III protein CHMP1A mediates secretion of sonic hedgehog on a distinctive subtype of extracellular vesicles. Cell Rep. 24:973-986.e8(2018)
Encyclopedic resources	Wikidata; Q114311752
Gene expression databases	GEO; GSM3192178 GEO; GSM3192179
Entry history
Entry creation	22-Sep-2022
Last entry update	10-Apr-2025
Version number	7