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Cellosaurus PC-3-AR (CVCL_C3HH)

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Cell line name PC-3-AR
Synonyms PC3-AR
Accession CVCL_C3HH
Resource Identification Initiative To cite this cell line use: PC-3-AR (RRID:CVCL_C3HH)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:644; AR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=30305041; DOI=10.1186/s12885-018-4848-x; PMCID=PMC6180441
Kasey Jividen, Katarzyna Z. Kedzierska, Chun-Song Yang, Karol Szlachta, Aakrosh Ratan, Bryce M. Paschal;
Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.
BMC Cancer 18:960.1-960.20(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C3HH
Encyclopedic resources Wikidata; Q114312649
Gene expression databases GEO; GSM3407115
GEO; GSM3407116
GEO; GSM3407117
GEO; GSM3407118
GEO; GSM3407119
GEO; GSM3407120
GEO; GSM3407121
GEO; GSM3407122
GEO; GSM3407123
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number8