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Cellosaurus SW480_6244R (CVCL_C3GM)

[Text version]
Cell line name SW480_6244R
Accession CVCL_C3GM
Resource Identification Initiative To cite this cell line use: SW480_6244R (RRID:CVCL_C3GM)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_90227; Selumetinib (AZD6244).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_C3GM
Encyclopedic resources Wikidata; Q114313074
Gene expression databases GEO; GSM3591768
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7