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Cellosaurus HEK293T AdipoR2 KO (CVCL_C3G1)

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Cell line name HEK293T AdipoR2 KO
Accession CVCL_C3G1
Resource Identification Initiative To cite this cell line use: HEK293T AdipoR2 KO (RRID:CVCL_C3G1)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:24041; ADIPOR2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=33444759; DOI=10.1016/j.bbalip.2021.158884
Mario Ruiz, Henrik Palmgren, Marcus Henricsson, Ranjan Devkota, Himjyot Jaiswal, Marcello Maresca, Mohammad Bohlooly-Y, Xiao-Rong Peng, Jan Boren, Marc Pilon;
Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids.
Biochim. Biophys. Acta 1866:158884.1-158884.12(2021)

Cross-references
Encyclopedic resources Wikidata; Q114311579
Gene expression databases GEO; GSE158834
Entry history
Entry creation22-Sep-2022
Last entry update14-Aug-2025
Version number9