Cellosaurus cell line Raji HLA-B*07:02 (CVCL

Cross-references
Cell line name	Raji HLA-B*07:02
Accession	CVCL_C3D5
Resource Identification Initiative	To cite this cell line use: Raji HLA-B*07:02 (RRID:CVCL_C3D5)
Comments	Population: African; Nigerian. Characteristics: Transduced with a lentiviral construct that contains a B2M-HLA-B fusion protein. Knockout cell: Method=ZFN; HGNC; 914; B2M. Transfected with: HGNC; 914; B2M. Transfected with: HGNC; 4932; HLA-B (allele B*07:02). Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_C3CD (Raji B2M KO)
Sex of cell	Male
Age at sampling	11Y
Category	Cancer cell line
Web pages	https://www.sigmaaldrich.com/catalog/product/sigma/hla001
Cell line databases/resources	cancercelllines; CVCL_C3D5
Encyclopedic resources	Wikidata; Q114312763
Entry history
Entry creation	22-Sep-2022
Last entry update	02-May-2024
Version number	6