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Cellosaurus A549 B2M KO (CVCL_C3CC)

[Text version]
Cell line name A549 B2M KO
Accession CVCL_C3CC
Resource Identification Initiative To cite this cell line use: A549 B2M KO (RRID:CVCL_C3CC)
Comments Population: Caucasian.
Knockout cell: Method=ZFN; HGNC; 914; B2M.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_C3CF (A549 HLA-A*01:01)CVCL_C3CG (A549 HLA-A*02:01)CVCL_C3CH (A549 HLA-A*03:01)
CVCL_C3CI (A549 HLA-A*11:01)CVCL_C3CJ (A549 HLA-A*24:02)CVCL_C3CK (A549 HLA-B*07:02)
CVCL_C3CL (A549 HLA-B*08:01)CVCL_C3CM (A549 HLA-B*15:10)CVCL_C3CN (A549 HLA-B*35:01)
CVCL_C3CP (A549 HLA-B*40:01)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Sigma-Aldrich

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135816
D5S81811
D7S8208,11
D8S117913,14
D13S31711
D16S53911,12
D18S5114,17
D21S1129
FGA23
Penta D9
Penta E7,11
TH018,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Web pages https://www.sigmaaldrich.com/catalog/product/sigma/hla003
Cross-references
Cell line databases/resources cancercelllines; CVCL_C3CC
Encyclopedic resources Wikidata; Q114310509
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5