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Cellosaurus SKOV3-GFP-STAT3 (CVCL_C3C1)

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Cell line name SKOV3-GFP-STAT3
Accession CVCL_C3C1
Resource Identification Initiative To cite this cell line use: SKOV3-GFP-STAT3 (RRID:CVCL_C3C1)
Comments Population: Caucasian.
Characteristics: Using ZFN a TagGFP2 construct was integrated at the N-terminus of the STAT3 gene (Sigma-Aldrich=CLL1139).
Genetic integration: Method=ZFN; Gene=FPbase; GJETS; TagGFP2 (Note=Green fluorescent protein derived from Aequorea macrodactyla GFP).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Sigma-Aldrich; CLL1139
Cell line databases/resources cancercelllines; CVCL_C3C1
Encyclopedic resources Wikidata; Q114313035
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7