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Cellosaurus UKRV-Mel-19b (CVCL_C399)

[Text version]
Cell line name UKRV-Mel-19b
Accession CVCL_C399
Resource Identification Initiative To cite this cell line use: UKRV-Mel-19b (RRID:CVCL_C399)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A720 ! UKRV-Mel-19a
CVCL_C400 ! UKRV-Mel-19c
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ECACC=13012536; ESTDAB=ESTDAB-231

Markers:
AmelogeninX
CSF1PO12
D3S135814,20
D5S81811
D7S82011,12
D13S31711,13
D16S53911
FGA22,23
TH019
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line collections (Providers) ECACC; 13012536
Cell line databases/resources cancercelllines; CVCL_C399
ESTDAB; ESTDAB-231
Encyclopedic resources Wikidata; Q54990606
Polymorphism and mutation databases Cosmic; 1846708
Cosmic; 2686521
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number19