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Cellosaurus I 4 (CVCL_C379)

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Cell line name I 4
Synonyms I4; Israel number 4; TE04; TE-04; TECHe002-A
Accession CVCL_C379
Resource Identification Initiative To cite this cell line use: I 4 (RRID:CVCL_C379)
Comments From: Technion - Israel Institute of Technology; Haifa; Israel.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0205.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*03:24
HLA-BB*35:02,38
HLA-CC*04,12
Class II
HLA-DQDQB1*01,06
HLA-DRDRB1*13,13
DRB3*01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; WiCell=te04

Markers:
AmelogeninX
CSF1PO12
D5S81811,12
D7S82012,13
D13S31712,14 (PubMed=16919167)
12,14,15 (WiCell=te04)
D16S53911,12
TH017,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/42
Publications

PubMed=16919167; DOI=10.1186/1741-7007-4-28; PMCID=PMC1601965
Richard Josephson, Gregory R. Sykes, Ying Liu, Carol J. Ording, Wei-Ning Xu, Xian-Min Zeng, Soojung Shin, Jeanne Frances Loring, Anirban Maitra, Mahendra Surendra Rao, Jonathan M. Auerbach;
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Barbara S. Mallon, Joshua G. Chenoweth, Kory R. Johnson, Rebecca S. Hamilton, Paul J. Tesar, Amarendra S. Yavatkar, Leonard J. Tyson, Kyeyoon Park, Kevin Gang Chen, Yang-Cheng Fann, Ronald Davies Graham McKay;
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line collections (Providers) WiCell; te04
Cell line databases/resources hPSCreg; TECHe002-A
NIHhESC; NIHhESC-13-0205
SKIP; SKIP001860
Encyclopedic resources Wikidata; Q54897063
Gene expression databases GEO; GSM856735
GEO; GSM862726
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number22